№ 7Differential Diagnostic Topics15 min read
Differential diagnosis of diarrhoea and constipation
1. Big picture
Diarrhoea and constipation are symptoms, not diagnoses. In the exam, the safest approach is:
First decide whether the patient is acutely ill or chronically symptomatic → identify red flags → classify the stool pattern → choose targeted tests.
The most important clinical split:
| Symptom | First exam question |
|---|---|
| Diarrhoea | Acute infectious/toxic vs chronic inflammatory/malabsorptive/functional? |
| Constipation | Functional/drug-induced vs obstruction/metabolic/neurologic? |
Always ask: Is there blood, fever, weight loss, dehydration, severe pain, anemia, nocturnal symptoms, or new onset after age 50? These are red flags.
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